Chemicals that have been identified as asthmagens, allergens or irritants by the authoritative organizations that we cite in the Red List should be disclosed if they are present in products so that consumers with sensitivities can avoid them. Tier 3: Asthmagens, allergens and irritants whose presence in products should be disclosed as potential allergens. Chemicals that have been designated as ecotoxicants by authoritative bodies are also placed on Tier 2. 
Chemicals that have only a single study indicating a human health concern are listed as emerging chemicals of concern and placed on Tier 2. Tier 2: Emerging chemicals of concern that should be avoided in products if possible. Chemicals that are not on authoritative lists but for which our literature review found multiple studies linking them with relevant human health effects are listed as Tier 1 chemicals and the citations are marked. 65 Program, etc.) as being harmful to human health are listed as Tier 1 chemicals and the relevant authoritative list is marked. Chemicals that are listed on an authoritative list (such as the International Agency for Research on Cancer (IARC), the National Toxicology Program (NTP), California’s Prop. Tier 1: Chemicals of concern that should not be used in personal care products or fragrances. 127 Tier 3 asthmagens, allergens and irritants whose presence in products should be disclosed so people suffering from these adverse health effects can avoid these chemicals of concern. 112 Tier 2 emerging chemicals of concern which should be avoided in products whenever possible. 241 Tier 1 chemicals of concern that should be prohibited from use in personal care products or as fragrance ingredients by manufacturers and retailers. 
Our most recent iteration of the Red List of Chemicals of Concern, released in August 2022, expanded to 480 chemicals used in beauty, personal care products, and/or as fragrance ingredients.
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